lacZ analysis showed that TtgR is a repressor of the ttgABC operon and the ttgR gene. EMSA showed that TtgR binds specifically to the ttgR-ttgABC intergenic region. DNase I footprinting assays identified the region bound by TtgR in the ttgR-ttgABC intergenic region.
Regulated genes for each binding site are displayed below. Gene regulation diagrams show binding sites, positively-regulated genes, negatively-regulated genes, both positively and negatively regulated genes, genes with unspecified type of regulation. For each indvidual site, experimental techniques used to determine the site are also given.
|Site sequence||Regulated genes||Gene diagram||Experimental techniques||TF function||TF type|