Curation Information

Regulation of the integrase and cassette promoters of the class 1 integron by nucleoid-associated proteins.;Cagle CA, Shearer JE, Summers AO;Microbiology (Reading, England) 2011 Oct; 157(Pt 10):2841-53 [21778209]
IHF [P0A6X7, view regulon]
Reported TF sp.
Escherichia coli str. K-12 substr. MG1655
Reported site sp.
Escherichia coli str. K-12 substr. MG1655
Created by
Erill Lab
Curation notes

Experimental Process

Involvement of IHF in regulation of integrase/cassette promoters shown by beta-gal with multiple promoter constructs. IHF binding is validated by EMSA footprints. Specific IHF sites are identified by PSSM search.

Transcription Factor Binding Sites


Gene Regulation

Regulated genes for each binding site are displayed below. Gene regulation diagrams show binding sites, positively-regulated genes, negatively-regulated genes, both positively and negatively regulated genes, genes with unspecified type of regulation. For each indvidual site, experimental techniques used to determine the site are also given.

Site sequence Regulated genes Gene diagram Experimental techniques TF function TF type
... ... intI1 aadA1 tnpM
Experimental technique details Beta-gal reporter assay - Experimental technique details EMSA (ECO:0001807) - Experimental technique details PSSM site search (ECO:0005659) - activator dimer