Curation Information

Mutation analysis of the Pseudomonas aeruginosa mvfR and pqsABCDE gene promoters demonstrates complex quorum-sensing circuitry.;Xiao G, He J, Rahme LG;Microbiology (Reading, England) 2006 Jun; 152(Pt 6):1679-86 [16735731]
MvfR [V6AIV4, view regulon]
Reported TF sp.
Pseudomonas aeruginosa UCBPP-PA14
Reported site sp.
Pseudomonas aeruginosa UCBPP-PA14
Created by
Kathryn Cronise
Curation notes

Experimental Process

MvfR was known to activate pqsA-E. EMSA was used to prove binding.

Transcription Factor Binding Sites


Gene Regulation

Regulated genes for each binding site are displayed below. Gene regulation diagrams show binding sites, positively-regulated genes, negatively-regulated genes, both positively and negatively regulated genes, genes with unspecified type of regulation. For each indvidual site, experimental techniques used to determine the site are also given.

Site sequence Regulated genes Gene diagram Experimental techniques TF function TF type
... ... pqsA pqsB pqsC pqsD pqsE ogt
Experimental technique details EMSA (ECO:0001807) - activator dimer