Curation Information

Publication
Widespread distribution of a lexA-regulated DNA damage-inducible multiple gene cassette in the Proteobacteria phylum.;Abella M, Erill I, Jara M, Mazón G, Campoy S, Barbé J;Molecular microbiology 2004 Oct; 54(1):212-22 [15458417]
TF
LexA [Q92PW3, view regulon]
Reported TF sp.
Sinorhizobium meliloti 1021
Reported site sp.
Sinorhizobium meliloti 1021
Created by
Erill Lab
Curation notes
-

Experimental Process

EMSA to validate binding, RT-PCR to show mitC induction.

Transcription Factor Binding Sites


GAGAACAAATACAGAACAT
GAGAACAAATACAGAACAT

Gene Regulation

Regulated genes for each binding site are displayed below. Gene regulation diagrams show binding sites, positively-regulated genes, negatively-regulated genes, both positively and negatively regulated genes, genes with unspecified type of regulation. For each indvidual site, experimental techniques used to determine the site are also given.

Site sequence Regulated genes Gene diagram Experimental techniques TF function TF type
GAGAACAAATACAGAACAT dnaE3, SMa0890, SMa0888,
... ... dnaE3 SMa0890 SMa0888 SMa0886 SMa5005 SMa0887
Experimental technique details EMSA (ECO:0001807) - Experimental technique details qRT-PCR [RNA] (ECO:0001808) - repressor dimer