Site information for: CodY in species Streptococcus pyogenes; genome accession: NC

Transcription Factor Binding Site Information

dbxref: CollecTF:EXPSITE_00024e90
Genome: Streptococcus pyogenes - NC_011375.1
TF: CodY [UniProtKB:B5XI03, view regulon]

Supporting Evidence

Binding site	Location	Publication	Experimental techniques used	Curation
AATATTCAGATAATT	+ [259882, 259896]	17510253	Experimental technique details Consensus search (ECO:0005624) Consensus search - ECO:0005624 This is a weak form of in-silico search, in which the consensus sequence for the motif is compared to genomic positions and the number of mismatches (between candidate site and consensus) is used as a measure of site-quality. - Experimental technique details qRT-PCR [RNA] (ECO:0001808) qRT-PCR [RNA] - ECO:0001808 Quantitative Reverse-Transcription PCR is a modification of PCR in which RNA is first reverse transcribed into cDNA and this is amplified measuring the product (qPCR) in real time. It therefore allows one to analyze transcription by directly measuring the product (RNA) of a gene's transcription. If the gene is transcribed more, the starting product for PCR is larger and the corresponding volume of amplification is also larger. -	873

Regulated genes

Regulated genes for each binding site are displayed below. Gene regulation diagrams show binding sites, positively-regulated genes, negatively-regulated genes, both positively and negatively regulated genes, genes with unspecified type of regulation. For each indvidual site, experimental techniques used to determine the site are also given.

Gene	Locus tag	Description
oppA	Spy49_0249	peptide ABC transporter substrate-binding protein
dacA	Spy49_0248c	Penicillin-binding protein 7
oppB	Spy49_0250	peptide ABC transporter permease
oppC	Spy49_0251	peptide ABC transporter permease
oppD	Spy49_0252	peptide transport ATP-binding protein oppD
oppF	Spy49_0253	peptide transport ATP-binding protein oppF